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Sylvester Opens New Clinic for Cancer Patients in Phase 1 Clinical Trials

From left, Jessica MacIntyre, M.S.N., ARNP, Stephen D. Nimer, M.D., Jaime R. Merchan, M.D., Dalissa Tejera, R.N., ARNP, and Yvonne Trang Dinh, CCRP.

From left, Jessica MacIntyre, M.S.N., ARNP, Stephen D. Nimer, M.D., Jaime R. Merchan, M.D., Dalissa Tejera, R.N., ARNP, and Yvonne Trang Dinh, CCRP.

Patients who participate in Phase 1 clinical trials at Sylvester Comprehensive Cancer Center now have a new clinic where they can get their specialized care in one convenient location. On Friday, April 20, Sylvester’s director, Stephen D. Nimer, M.D., and the director of Phase 1 clinical trials, Jaime Merchan, M.D., cut the ribbon at the new clinic located on the third floor.

“This is the beginning of us becoming a great and important Phase 1 center in the country and in the world, where we will be able to bring the best and most innovative treatments and especially a lot of hope for our patients,” Merchan, who is also associate professor of medicine, said at the opening.

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Priyamvada Rai, Ph.D.

Dr. Priyamvada Rai of Sylvester Named to Tumor Cell Biology Study Section

Sylvester Comprehensive Cancer Center researcher Priyamvada Rai, Ph.D., has been appointed to the Tumor Cell Biology Study Section of the Center for Scientific Review at the National Institutes of Health. Being named a member of the study section is a distinct honor and “a unique opportunity to contribute to the national biomedical research effort,” the director of the Center for Scientific Review said in his letter to Rai.

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BC-3 cells were stained with DAPI, anti-vFLIP, anti-CADM1, and cholera toxin B conjugated with red fluorescence to detect GM-1 and subjected to confocal microscopy.

Sylvester Researchers Identify Protein that Triggers Virus-Mediated Chronic Inflammation and Cancers

Viruses are linked to approximately 12 percent of all cancers and are associated with chronic inflammation. Sylvester Comprehensive Cancer Center researchers Noula Shembade, Ph.D., Richard Hunte and colleagues honed in on what activates that process. They found the human protein CADM1 interacts with Kaposi’s sarcoma viral proteins and promotes inflammation that can result in development of certain cancers.

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From left, Javier Flores, M.D. ’95, Elsy Carbot-Flores, M.D. ’95, Francisco “Frank” Flores, M.D. ’95, Hilit F. Mechaber, M.D. ’95, Ayleen Pinera-Llano, M.D. ’95, and Oscar Sosa, M.D. ’95.

Mentors Help Medical Students Focus in on a Specialty

In addition to hours of class work, clinical training, and endless amounts of studying, medical students also face the challenge of focusing in on which medical specialty they would like to pursue. The Office of Student Services tries to make that task a little easier each year by hosting numerous events, including the annual Career Advising Dinner.

Read more about the Career Advising Dinner »

From left, Ashok, Saluja, Ph.D., Vrishketan Sethi, M.B.B.S., and Vikas Dudeja, M.D. Video & Photo Gallery

A New Take on Immunotherapy: Gut Microbes and Tumor Growth

Investigating the microbiome has provided new insights into infection control, metabolism and mental health. It may also play a significant and surprising role in cancer. Scientists at Sylvester Comprehensive Cancer Center have shown that depleting the gut microbiome reduces tumor growth and metastases in models of pancreatic cancer and melanoma and slows metastases in colon cancer.

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Antibody ‘Cocktail’ Can Prevent Zika Infection But Is Not Effective for Treatment of Fetuses, Say Miller School Researchers

A “cocktail” of monoclonal antibodies that can prevent Zika virus (ZIKV) infection in primates was not effective for treatment of fetuses, according to a new collaborative study led by a University of Miami Miller School of Medicine research team. The team is now working on engineering the antibodies to redirect the therapies to the fetus.

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