Contact Information:

Anil Lalwani
Director of Biotechnology Resources

Campus Address (For Interoffice Mail):
University of Miami | Medical Campus
Dominion Tower (12th Floor)
1400 NW 10th Ave.
Miami, Fl. 33136


Miami, Florida 33136
Tel: 305-243-9815 (office)

Laboratory Research Resources

* Resources listed in red text are being planned and will be available soon

Resource  Types
Available Resources  (with affiliation where appropriate)
Biostatistics
Biorepository
Bioinformatics and Computing
Comparative Pathology
Electron Microscopy (EM)
Flow Cytometry and Cell Sorting
Freezer Facility
Freezer Program
High Content Screening
Histology
Imaging (analytical, confocal, light, stereo, etc)
MRI Resources (for animal & tissue)
Molecular Analysis & "Omics" Technologies
Monoclonal Antibody Resources
Pharmacokinetics (SCCC)
Phosphoimagers
Transgenic and Gene Knockouts
Veterinary Resources
Viral Vectors
X-ray Crystallography
Other
 
     
     
     
     
     
     

Biostatistics

   

Several Biostatistics related resources are available for investigators.

   
The Biostatistics Core at the UM/ Sylvester Comprehensive Cancer Center serves as resource for Cancer center members.

 

Contact:
Dr. Isildinha Reis
or
Dr. Gail Walker

The following cores at the Miami Institute for Human Genomics serve as resources for various statistical and epidemiology functions focusing on human genetic studies:

 

Contact:

 

Dr. Mike Schmidt

 

Susan Slifer

     

The Biostatics Center (BSC) at Bascom Palmer Eye Institute provides assistance with ocular associated research and clinical study design, data management and analysis.


  Contact:
Joyce Schiffman
Biostatistics Core is a new university wide resource in the planning stages.   Contact:
TBA
   
  top
     

     
Biorepository    

The Tissue Banking Core Facility at the UM/ Sylvester Comprehensive Cancer Center serves as a resource for Cancer center members.


  Contact:
Dr. Sean Scully

A Brain and Tissue Bank for Developmental Disorders distributes tissue in various preparations to investigators.

  
  Contact:
Brain and Tissue Bank Coordinator

A Brain Biorepository also distributes brain tissue in various preparations to investigators.


  Contact:
Submit a request

The MIHG Biorepository core at the Miami Institute for Human Genomics serves as a resource for sample handling, storage and informatics services related to IRB approved clinical research study samples.


  Contact:
MIHG bank
   
  top
     

     
Bioinformatics & Computing    

The newly created Center for Computational Sciences (CCS) is a university-wide enterprise that is committed to working with you to advance your research. CCS focuses its efforts on catalyzing interdisciplinary computational science among all divisions, departments, schools and colleges involved in the research sciences and engineering.

CCS is developing various initial cross-disciplinary programs that together span the life sciences, earth sciences, engineering, and the high tech world.  These are in Bioinformatics, Physical Sciences and Engineering, Computational Chemistry, Data Mining and Visualization.

The infrastructure for these programs is provided via:

  • High Performance Computing Core, and
  • Scientific Software Engineering Core

The mission of the Bioinformatics Program of CCS is to spearhead bioinformatics capacity at the University of Miami for all biological and medical applications.  CCS is setting up a Bioinformatics Toolkit (website in the works) which will house almost all freely available genomic and genetic databases and web tools, as well as several licensed tools that will be made available to users under a Software Access Policy.

 
  Contact: Bioinformatics Program

The Informatics Core at the UM/Sylvester Comprehensive Cancer Center provides its members and affiliates with Systems Development and Support as well as Network Management and Personal Computing services.


  Contact:
Dr. Dido Franceschi

The new Genomic Medicine Registry assists researchers to get collections started by providing help with informatics, logistics and funding. This resource accelerates or jump starts the process by providing the necessary tools, methods and expertise to get collections going.


  Contact:
Dr. David Seo
   
  top
     

     
Comparative Pathology    
The laboratory of the Division of Comparative Pathology provides routine and specialized diagnostic testing to investigators utilizing animals in their research projects. Faculty members can assist the investigators with information regarding study design, sample collection, and test interpretation. Frozen sectioning services are also available.   Contact
Lab Manager
   
  top
     

     
Electron Microscopy (EM)    
The EM Core is a university wide core.  It is a conventional Transmission Electron Microscopy facility with associated sample processing services like embedding, sectioning, etc.   Contact
Peggy Bates
An Electron Microscope is available for investigators affiliated with The Miami Project to Cure Paralysis.   Contact
Dr. Mary Bunge
   
  top
     

     
Flow Cytometry & Cell Sorting    

The Flow Cytometry Core Facility managed by UM/ Sylvester Comprehensive Cancer Center serves as the central campus wide resource. The Flow Cytometry Core Facility has recently added new cell sorting capabilities that will allow investigators working with potentially pathogenic agents to access flow cytometry and cell sorting for live and unfixed material.


 

Contact:
Huw S. Kruger Gray
or
James Phillips

At the Flow Cytometry facility managed by Diabetes Research Institute (DRI), service is prioritized to DRI faculty and staff. Access for all other investigators is subject to instrument availabilty.


  Contact
Dr. Oliver Umland

A new clean room based high speed clinical cell sorting and processing facility operated under cGMPs is planned for the new home of the Interdisciplinary Stem Cell Institute (ISCI) in the new wet lab building.


  Contact
Dr. Ian McNiece
These three (3) facilities (SCC + DRI + ISCI) have formed an alliance with the mission and dedication to provide all investigators at the Miller School of Medicine access to comprehensive and cost-effective services, applications and technologies for analysis and cell sorting needs.
   
  top
     

     
Freezer Program    
A freezer program service operated by the DNA Core Lab provides discounted prices and free shipping on various supplies and reagents. The lab also acts as a gateway for outsourcing oligonucleotide synthesis.   Contact:
Erica Alecio
or
Jessica Eghba
   
  top
     

     
High Content Screening Core (new)    
A new High Content Screening Core is now open at the Miami Project to Cure Paralysis. The HCS Core uses the cellomics platform to provide multiplexed functional screening and imaging services to generate high information content on cell-bases assays.   Contact:
Yan Shi
   
  top
     

     
Histology    
Histology services such as paraffin embedding, tissue sectioning, histological stains are available at several locations on campus.    

The EM Core provides routine embedding, sectioning and histological staining services.

 
  Contact
Peggy Bates

The Histology Research Core Facility managed by UM/ Sylvester Comprehensive Cancer Center provides routine histology services.

 
  Contact
Mariana Nunez

The Histology Core managed by Bascom Palmer Eye Institute also provides routine histology services. The Core is open to UM Faculty, however, priority is given to NEI funded investigators.

 
  Contact
Magda Celdran
Histology services for investigators affiliated with the Miami Project to Cure Paralysis are available by contacting Dr. Beata Frydel.

  Contact
Dr. Beata Frydel.
Frozen sectioning services are also available at the laboratory of the Division of Comparative Pathology.   Contact
Lab Manager
   
  top
     

Imaging & Microscopy    
Several Imaging resources are available on campus.    

The Analytical Imaging Core Facility is UM's open access light microscopy and image analysis core facility that offers comprehensive facilities, instrumentation, training and consultation services. Capabilities include: confocal microscopy, fluorescence microscopy, laser scanning cytometry, laser capture microdissection, fluorescence and/or DIC time-lapse, general microscopy and image analysis.

 
  Contact
Dr. George McNamara

The Imaging Core managed by Bascom Palmer Eye Institute also provides confocal and laser scanning microscopy, image analysis, stereo and time-lapse microscopy (FRET). The Core is open to UM Faculty, however, priority is given to NEI funded investigators.


  Contact:
Gabriel Gaidosh

Imaging services for investigators affiliated with the Miami Project to Cure Paralysis are available by contacting Dr. Beata Frydel.


  Contact
Dr. Beata Frydel

Fluoroscopy and angiography imaging services are available at the Endovascular Research Center.

  Contact
Dr. Baruch Lieber
   
  top
     

     
Magnetic Resonance Imaging (MRI)    

The High-Field MRI Bio-Medical Research Facility is a university wide core. It offers MRI and Spectroscopy capabilities using a small bore Bruker Biospin 4.7 Tesla high field MRI system.


  Contact:
Dr. Kyle Padgett
A large bore, 1.5 Tesla Siemens Sonata MRI equipped with Syngo software and dedicated coils and and peripheral is available for larger animal studies through Interdisciplinary Stem Cell Institute (ISCI).

  Contact:
Dr. Joshua Hare
   
  top
     

     
Molecular Analysis & “Omics” Technologies    
Several contemporary bioscience research tools and technologies are available on the Medical campus.    
Two (2) new cores and the existing Microarray Core Facility have been organized under the Miami Institute for Human Genomics (MIHG).    
  • The Genotyping Core provides high throughput Illumina system based genotyping as well as Sequenon’s MassARRAY system for intermediate genotyping. ABI 7900 HT Taqman based sequencing is also available.
  Contact:
Anna Konidari
  • The Sequencing Core provides both high throughput and intermediate throughput sequencing services via ABI 3730 and 3130 capillary sequencers. Additional services such as Copy Number Variation (CNV) analysis are also provided using Illumina and Nimblegen systems.
 

Contact:
Bill Hulme

  • The Microarray Core provides services and expertise for microarrays and related technologies including Agilent and Affymetrix systems. A broad range of services are offered such as sample preparation (DNA, RNA) and QC (using Agilent Bioanalyzer and NanoDrop quantification), hybridization as well as comprehensive microarray data analysis using a variety of bioinformatics tools including Genespring.
  Contact:
Dr. Lubov Nathanson

The Oncogenomics Core Facility managed by UM/ Sylvester Comprehensive Cancer Center also provides the latest platforms and technology based molecular analysis services.

 
  Contact
Dr. Toumy Guettouche

A molecular and genetic analysis resource for investigators with a particular focus on cardiac diseases is available at the Cardiovascular Genetics Core Lab.

 
  Contact
Dr. Nanette Bishopric
Proteomics and mass spectrometry services are offered through the Proteomics Core Facility managed by UM/ Sylvester Comprehensive Cancer Center. This resource serves as a portal to the Proteomics Core Facility at Florida Atlantic University. UM investigators can utilize the benefits of this cross-university collaboration.   Contact
Dr. Toumy Guettouche
   
  top
     

     
Monoclonal Antibodies (coming soon)    
The Biologics Modifiers Core at the W.H. Coulter Center (WHCC) is planning the creation of Monoclonal Antibody production and purification services. The core will provide milligram quantities of antibodies to UM investigators.   Contact:
Dr. Pirouz Daftarian
   
  top
     

     
Pharmacokinetics    
The Pharmacokinetics Core Facility managed by UM/ Sylvester Comprehensive Cancer Center provides comprehensive analytical chemical analysis and pharmacology research for UM investigators.   Contact:
Caihong Mou
   
  top
     

     
Phosphoimagers    
The Phosphoimager Core Facility provides imaging and analysis of radioactive samples on a Storm 840 PhosphorImager. Chemiluminesce and visible imaging services are also available.   Contact:
Dr. Mary Lou King
 The Imaging Core managed by Bascom Palmer Eye Institute has a Typhoon 9410 Trio+ Phosphoimager capable of various configurations for radioactivity and two-color fluorescence-labeled tissues, 1D and 2D gels, plates and arrays.

Contact:
Gabriel Gaidosh

   
  top

     
Transgenic & Gene Knockouts    

The Transgenic Animal Core Facility at UM/Sylvester uses powerful transgenic/gene knockout technologies to study the function of genes in vivo. The core produces transgenic mice and targeted-mutant mice. It provides experimental design and support for investigators using this technology to apply to their research. Genetically modified mouse models are essential tools in many areas of biomedicine and basic research.

Transgenic mice are produced by injecting one-cell embryos with foreign DNA, resulting in the random integration of genes into the mouse genome. Alternatively, targeted-mutant mice (also known as "knockout" and/or "knockin" mice) are produced by injecting mouse blastocyst with pluripotent embryonic stem (ES) cells, whose DNA has undergone homologous recombination with exogenous DNA, resulting in targeted changes at specific Ioci. Conditional knock-outs are being generated using C57BL/6 derived ES cell and isogenic genomic DNA incorporating cre/loxP and frt/flp recombinase systems.

  Contact:
Dr. Peter Sobieszczuk
   
  top
     

     
  Veterinary Resources    

The Division of Veterinary Services (DVR) is a centralized animal care service center that provides professional and technical services to investigators who use animals in their research.

DVR staff can provide consultative and collaborative assistance to investigators by identifying appropriate animal models, evaluating nutritional needs and assessing caging and other environmental enrichment requirements.

  Contact
Dr. Linda Waterman
   
  top
     

     
Viral Vectors Core    
A new Viral Vector Core is now open at the Miami Project to Cure Paralysis. The VV Core provides investigator requested AAV and Lentivirus particles. Stocks of most commonly used AAV and Lentiviral vectors (GFP, RFP, etc) are also be available.   Contact:
Dr. Anthony Oliva
   
  top
     

     
X-ray Crystallography    
Comprehensive instrumentation and expertise to determine 3-D structures of proteins and other macromolecules are available through Dr. Arun Malhotra’s Laboratory at the Department of Biochemistry and Molecular Biology.   Contact
Dr. Arun Malhotra
   
  top
     

     
Other Resources    

Endovascular Research Center: animal surgery and testing using endovascular devices (stents, coils, grafts, etc) or requiring fluoroscopy or angiography imaging services can be arranged at the Endovascular Research Center.

  Contact
Dr. Baruch Lieber
   
  top